Organic disulfides
Medchemexpress LLC HY-D0844 100mg Medchemexpress, Glutathione oxidized CAS:27025-41-8 Purity:>98%
Medchemexpress, HY-D0844 100mg Glutathione oxidized CAS:27025-41-8 Glutathione oxidized is produced by the oxidation of glutathione which is a major intracellular antioxidant and detoxifying agent. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Sigma Aldrich Fine Chemicals Biosciences Dimethyl disulfide natural250G
Dimethyl disulfide natural250G
Medchemexpress LLC (R)-NX-2127 | 3024312-52-2 | 98.9% | 719.83 | C39H45N9O5 | 10 MG
(R)-NX-2127 is the R-isomer of a Bruton's tyrosine kinase (BTK) PROTAC degrader supplied as a high-purity solid for preclinical research. The compound is intended for use in studies of BTK degradation and related cellular pharmacology; consult the supplier product page and SDS for handling and storage details.
- R-isomer of a BTK PROTAC degrader
- High reported purity (98.93%)
- Molecular weight 719.83
- Chemical formula C39H45N9O5
- Solid, light yellow to yellow appearance
- Recommended storage: 4°C protected from light; in solvent -80°C (6 months) or -20°C (1 month)
- Intended for preclinical BTK degradation and cellular assays
Medchemexpress LLC PROTAC degrader targeting Bruton's tyrosine kinase (BTK) | 2416131-46-7 | 99.7% | 719.83 | C39H45N9O5 | 10 MG
NX-2127 is an orally bioavailable PROTAC degrader that targets Bruton's tyrosine kinase (BTK). It induces proteasomal degradation of BTK, shows activity against BTK C481S resistance mutants, degrades IKZF1 and IKZF3 transcription factors, and has demonstrated cellular and in vivo preclinical activity while promoting T cell activation and IL-2 production.
- Orally bioavailable PROTAC degrader of BTK.
- Induces proteasomal degradation of BTK and reduces BTK signaling.
- Active against BTK C481S resistance mutants in cellular models.
- Degrades IKZF1 and IKZF3, providing immunomodulatory effects.
- Stimulates T cell activation and increases IL-2 production in primary human T cells.
- Demonstrated efficacy in preclinical in vivo models.
Medchemexpress LLC Hydroxyethyl disulfide | 1892-29-1 | MFCD00002906 | 98.8% | 154.25 g/mol | C4H10O2S2 | 10 G
Hydroxyethyl disulfide is a small-molecule laboratory reagent used in biochemical research. It is reported to interact with thymidylate synthase pathways and is provided with supporting documentation such as a certificate of analysis and safety data sheet. The compound is commonly used as a reagent or intermediate in chemical and biochemical studies.
- Purity 98.8% (reported)
- Cas number 1892-29-1
- Molecular formula C4H10O2S2
- Molecular weight 154.25 g/mol
- Available as a 10 G package
Medchemexpress LLC N N-Dicyclohexyl-2-b 25g
N N-Dicyclohexyl-2-benzothiazolesulfenamide is a compound with reproductive and developmental toxicity that can affect body weight gain reproductive organ weight and multiple reproductive and developmental indicators in rats
Medchemexpress LLC N N-Dicyclohexyl-2-b 100g
N N-Dicyclohexyl-2-benzothiazolesulfenamide is a compound with reproductive and developmental toxicity that can affect body weight gain reproductive organ weight and multiple reproductive and developmental indicators in rats
eMolecules Medchem Express / SPDP-C6-NHS ester / 25mg / 746319267 / HY-124377 / / 158913-22-5 / MFCD00083163 / 425.520 / C18H23N3O5S2
Medchem Express / SPDP-C6-NHS ester / 25mg / 746319267 / HY-124377 / / 158913-22-5 / MFCD00083163 / 425.520 / C18H23N3O5S2
eMolecules Ambeed / 2-(4-Nitrobenzamido)acetic acid / 1g / 586036432 / A703345 / / 2645-07-0 / MFCD00007349 / 224.172 / C9H8N2O5
Ambeed / 2-(4-Nitrobenzamido)acetic acid / 1g / 586036432 / A703345 / / 2645-07-0 / MFCD00007349 / 224.172 / C9H8N2O5
TARGETMOL CHEMICALS INC NX-2127 1MG
Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. NX-2127 (ETX2514 Triethylamine) is an orally active BTK inhibitor that induces degradation of mutant BTKC481S in cells.NX-2127 has potent antiproliferative activity and inhibits the proliferation of BTKC481S mutant TMD8 cells.NX-2127 potently catalyzes the degradation of Ikaros (IKZF1) and Aiolos (IKZF3) at 25 nM and 54 nM, respectively. NX-2127 is associated with the immune system, stimulating T cell activation and increasing IL-2 production in primary human T cells. Purity 98.11%
Selleck Chemical LLC NX-2127-E1381-25MG
NX-2127 is a unique potent inhibitor of BTK that prevents its functions by catalyzing the ubiquitylation and proteasomal degradation of BTK rather than via direct binding NX-2127 stimulates T cell activation and increases IL-2 production in primary human T Cells
Selleck Chemical LLC NX-2127-E1381-100MG
NX-2127 is a unique potent inhibitor of BTK that prevents its functions by catalyzing the ubiquitylation and proteasomal degradation of BTK rather than via direct binding NX-2127 stimulates T cell activation and increases IL-2 production in primary human T Cells